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The
human brain is a fascinating and complex organ. The brain is so complex
that it is not possible that one or two isolated substances could
possibly optimize nutrition for it. That is why Serious Brain Enhancer
contains a combination of high nutrient foods and food extracts to
provide some of the most complete and comprehensive support available
anywhere. An optimally functioning brain is needed for an optimally
functioning life. An optimally functioning brain has an excellent
memory, can learn, can focus, is not depressed, and maintains proper
mood. Note: Other than a wild salmon extract, all glandulars in this Food product are ovine from New Zealand.
Acerola Cherry is one of the most vitamin C dense Foods.
Not only does it have free radical scavenging abilities, it also has
been shown to increase the antioxidant abilities of some other foods
(1).
“Alpha-Lipoic Acid, also known as
thioctic acid…is a potent biological antioxidant” (2). Studies have
concluded it helped aged mice improve memory (3), protects the brain
from cerebral ischemia-induced reperfusion injury (4), that it
counteracted glycollate-induced free radical toxicity (5), and that it
had neuroprotective effects against ischemia (6). “Alpha lipoic acid is
actually the most efficient way to help the body produce glutathione
(7).
Choline is a required nutrient which is needed for the normal development of memory (8).
Corn Silk is normally used for the kidneys or liver (9), but appears to have synergistic properties for brain support.
Deoxyribonucleic acid (DNA), along with ribonucleic acid (RNA), act as ‘memorigenics’ (10).
Eleuthero Root, once known as Siberian Ginseng,is
an herbal adaptagen. “Siberian ginseng is used as a tonic for
invigoration and fortification in times of fatigue and debility or
declining capacity for work and concentration, and during
convalescence” (9).
Flaxseeds contain
30-45% fatty oil--this oil consists primarily of linolenic acid
(40-70%), linoleic acid (10-25%) and oleic acid (13-30%) (9). “Flaxseed
oil can provide the body with ample quantities of the essential fatty
acid omega 3, which is transmuted into another fatty acid and
ultimately provides nourishment for the brain cells” (11).
Grape Seed Extract provides
the richest source of oligomeric proanthocyanidins (OPCs) that is able
to pass the blood brain barrier. Some consider OPCs an ‘anti-stroke’
nutrient which “keeps collagen elastic and softens blood platelets”
(11). OPCs have anti-oxidant effects (2); OPCs enhance the brain by
encouraging vascular efficiency.
Inositol “can help alleviate anxiety by acting as a natural Valium minus the side effects” (11).
L-Carnosine
has antiglycation effects and has been proposed as an ‘anti-aging drug’
(12). Some believe it may be helpful to prevent complications
associated with Alzheimer’s and other dementias (12).
L-Methionine is
an essential sulfur amino acid which easily passes the blood-brain
barrier where it is converted into S-adenosylmethionine (SAMe) (13). A
study involving Parkinson’s found that it improved activity level, ease
of movement, rigidity, mood, sleep, attention span, concentration,
voice, and muscular strength (14).
L-Tyrosine has an effect on nerve impulse transmission and may “improve vigilance and lessen anxiety” (15).“Tyrosine
and phenylalanine promote the production of dopamine within the brain,
a vital compound responsible for regulating the operation of
neurotransmitters” (11) (phenylalanine is naturally in ovine brain
(16)).
“Lecithin is a type of lipid that
is needed by every cell in the body…The protective sheaths surrounding
the brain are composed of lecithin…Lecithin consists mostly of the B
vitamin choline, and also contains linoleic acid and inositol” (17) in
the forms of phosphatidylcholine and phosphatidylinositol. “This
nutrient…improves brain function” (17). It also contains
phosphatidylethanolamine.
OvineGlandulars products are a Food
believed by their proponents to provide nutritional support for the
corresponding gland in the body (18-21). Glandular organs have been apart
of the human diet for centuries (22). Glandulars contain nutritional
peptides, enzymes (when freeze or vacuumed-dried), and other tissue
substances (18-21). Glandular substances may reduce aspects of cellular
atrophy, degeneration, decreases in tissue elasticity, and other
negative aspects associated with aging (21). Brain glandulars contain
“specific brain cell activators” (23) and have been advised for
slowness of thought, loss of memory, uncontrolled mental activity,
nightmares, mental retardation, and epilepsy (24,25). A double-blind
study involving bovine-brain derived phosphatidylserine found it was
able to improve both behavior and cognition in elderly people with
cognitive decline (26). “...phosphatidylserine enhances the ability of
enzymes in membranes of nerve cells to relay messages in and out of the
cells. This product can improve memory in older adults, and can
ameliorate symptoms of depression” (11). Research suggests that the
glandular source phosphatidylserine is more effective than soy isolate
sources (27). Pituitary glandulars have been used for nearly a century
to provide nutritional support for people with problems such as mental
retardation, slowed growth, Down syndrome, epilepsy, loss of memory,
developmentally delayed children, premature senility and other
situations (23,28). Trachea naturally supplies chondroitin-sulfate A.
Early research indicated that ruminant source glandulars (bovine,
ovine) were better for humans than animal sources (21,29). Ovine brain
tissue naturally contains about 1.0% methionine, 2.4% phenylalanine,
.5% tryptophan and 1.8% tyrosine by dry weight (16); other ovine glands
have a similar amino acid profile.
Selenium in Food has been found to be about twice as well retained as other forms (30).
Vitamin B6 deficiencies
of vitamin B6 can eventually lead to symptomatic memory problems (11).
Higher plasma levels of vitamin B6 do seem to correlate to better
memory in the elderly (31). Even children with learning problems have
been reported to respond to vitamin B6 (11). Vitamin B12 can prevent certain dementias and assist mood (2,32,33). Vitamins B6, B12, and folate all appear to assist memory function (2,11,32,33).
Vitamin E in Food
has about 4.0 times the free radical scavenging strength of synthetic,
non-food vitamin E (34). Vitamin E has antioxidant abilities and
appears to have positive effects on preventing certain forms of
cognitive decline (2,33). Food Vitamin E has
been proven to have 12 micro moles per gram T.E. of lipophilic ORAC
(oxygen radical absorbance capacity) [34]—ORAC is essentially a
measurement of the ability to quench free radicals (antioxidant
ability). It is interesting to note that so-called “natural” forms
(like succinate) such as do not even work like Food Vitamin E—Even
the PDR notes, “d-Alpha-Tocopherol succinate itself has no antioxidant
activity” [35], so why would anyone want that for their vitamin E
supplement?
It is no wonder, once they know the science, that professionals interested in optimal natural health recommend Food Serious Brain Enhancer as the preferred Food source for comprehensive brain nutrition.
Serious Brain Enhancer Video
Unlike many so-called “natural” formulas, Serious Brain Enhancer
is only comprised of foods, contains no synthetic USP vitamins or
isolated mineral salts, but only contains foods, food concemtrates, and
food extracts.
Numerous university studies have
concluded that supplements containing food nutrients are better than
USP isolates. Food nutrients are better because they contain important
enzymes, peptides, and phytonutrients CRITICAL to the UTILIZATION of
vitamins and minerals which are not present in isolated USP nutrients.
Published research has concluded that food vitamins are superior
synthetic/USP vitamins.
Suggested use: 1-9 capsules per
day or as recommended by your health care professional. Adjust usage
according to nutritional lifestyle requirements.
REFERENCES
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Hwang J, Hodis HN, Sevanian A. Soy and alfalfa phytoestrogen extracts
become potent low-density lipoprotein antioxidants in the presence of
acerola cherry extract. J Agric Food Chem. 2001;49(1):308-314
- Sheldon S, Rorvik D, eds. PDR for Nutritional Supplements. Medical Economics, Montvale (NJ), 2001
-
Stoll S, et al. The potent free radical scavenger alpha-lipoic acid
improves memory in aged mice. Pharmacol Biochem Behav, 46(4):799-805,
1993
- Panigrahi M, et al. Alpha-lipoic acid
protects against reperfusion injury following cerebral ischemia in
rats. Brain Res, 717(1-2):184-188, 1996
-
Sumathi R, et al. Effect of DL alpha-lipoic acid on tissue lipid
peroxidation and antioxidant systems in normal and glycollate treated
rats. Pharmacol Res, 27(4):309-318, 1993
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Cao X, Phillis JW. The free radical scavenger alpha-lipoic acid,
protects against cerebral ischemia-referfusion injury in gerbils. Free
Radical Res, 23(4):365-370, 1995
- Balch J. The hidden epidemic. Healthy Living, 32:1-7, 2000
- Zeisel SH. Choline: Needed for normal development of memory. J Am Coll Nutr, 19(5):528S-531S:2000
- Gruenwald J, et al. PDR for Herbal Medicines, 2nd ed. Medical Economics, Montvale (NJ), 2000
- Null G. The Clinician’s Handbook of Natural Healing. Kensington, New York, 1997
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Dukic-Stefanovic S, Schinzel R, Riederer P, Munch G. AGES in brain
ageing: AGE-inhibitors as neuroprotective and anti-dementia drugs?
Biogerontology. 2001;2(1):19-34
- Werbach MR. Textbook of Nutritional Medicine. Third Line Press, Tarzana (CA), 1999
- Smythies JR Halsey JH. Treatment of Parkinson’s disease with l-methionine. South Med J, 77:1577, 1984
- Specific nutrients aid in high-performance activity. Nutr Week, June 4, 1994:7
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Lamb, variety meats and by-products, brain, raw. NDB No. 17185. USDA
National Nutrient Database for Standard Reference, Release 16-1 (2004)
- Balch JF, Blach PA. Prescription for Nutritional Healing, 2 nd ed. Avery Publishing Group, Garden City Park (NY), 1997
- DeCava JA. Glandular supplements. Nutrition News and Views 1997; 1(3):1-10
- Burns D. Growing scientific evidence support glandular therapy. Digest of Chiropractic Economics, Nov/Dec 1987:74-79
- Schwartz EF. Glandular therapy. American Chiropractor, Jan/Feb 1983:14-18
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Lee R, Hanson W. Protomorphology: The Principles of Cell
Auto-Regulation. Lee Foundation for Nutritional Research, Milwaukee,
1947
- Dunbar R. Foraging for nature’s balanced diet. New Scientist August 31, 1991:25-28
- Lee R. Therapeutic Food Manual, Lee Foundation for Nutritional Research, Milwaukee, circa 1950;14
- Lee R. Brain Cytotrophin. Lee Foundation for Nutritional Research, Milwaukee, circa 1950
- Profiles in Nutritional Progress. Rubicon Productions, Bakersfield, 1993
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Cenacchi T, et al. Cognitive decline in the elderly: a double-blind
placebo-controlled multicenter study on the efficacy of
phosphatidylserine administration. Aging Clin Exp Res 5:123-133, 1993
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Dean W, Morgenthaler J, Fowkes SW. Phosphatidylserine. In Smart Drugs
II: The Next Generation. Smart Publications, Petaluma (CA), 1993:75-80
- Harrower HR. An Endocrine Handbook. Harrow Laboratory, Glendale, 1939
- Nuttail Dr . Blood Immunity and Blood Relationships. Cambridge University Press, London, 1904
- Biotechnology in the Feed Industry. Nottingham Press, UK, 1995: 257-267
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Riggs K, et al. Relations of vitamin B-12, vitamin B-6, folate, and
homocysteine to cognitive performance in the Normative Aging Study. Am
J Clin Nutr 63:306-314, 1996
- Shils M, Olson J, Shine M, Ross A, eds. Modern Nutrition in Health and Disease, 9th ed. William & Wilkins, Balt.,1999
- Solfrizzi V, Panza F, Capurso A. The role of diet in cognitive decline. J Neural Transm. 2003;110(1):95-110
- ORAC Test by Brunswick Laboratories, Wareham (MA), February 2006
- Sheldon SS, Rorvik D, ed. PDR for Nutritional Supplements, 1 st ed. Medical Economics, Montvale (NJ), 2001
Some of these studies (or citations) may not conform to peer review
standards, therefore, the results are not conclusive. Professionals
can, and often do, come to different conclusions when reviewing
scientific data. None of these statements have been reviewed by the FDA. All
products distributed by Doctors’ Research, Inc. are nutritional and are
not intended for the treatment or prevention of any medical condition.
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