Bone and joint health are nutritionally complex [1-3]. Many Food nutrients, other than simply calcium, are required for proper bone and joint health [1-4]. Manganese deficiency can contribute to disorders of calcium metabolism and can cause skeletal abnormalities [1]. Boron deficiency can lead to a weakening of bone composition, structure, and strength [1]. Vitamin D is involved in bone formation and the calcium metabolism. Vitamin C is involved in collagen formation, which is necessary for joint health; it also improves the absorption of calcium [1]. Vitamin K, boron, copper, phosphorus, and potassium also help the body retain calcium [1]. Considered to be non-essential until 1972, silicon has an important role in bone and cartilage collagen biosynthesis and “is involved in the organic phase in the series of events leading to calcification” (plus it is necessary for healthy bones, skin, hair, and nails) [1].

Research shows that Food nutrients are better than isolated USP vitamins [e.g. 5-7] or inorganic mineral salts or mineral chelates [e.g. 8-9]. Consumption of isolated calcium is unnatural and is why many feel that calcium needs to be taken with magnesium, vitamin D, phosphorus, and other nutrients which are in Food Cal-Mag Complex (also, factors other than calcium help work with calcium to prevent osteoporosis [1-3]). Research has shown that there are low incidences of osteoporosis in cultures where people consume 300 mgs of Food calcium per day or less from vegetable sources, [2-3] (Food Cal-Mag Complex is a vegetable source of calcium). This appears to be because the other, non-calcium, nutrients in plants play important roles in bone development [1-4]. Interestingly, though the consumption of vegetables and fruits is positively correlated with increasing bone density [2-4], mainstream research has concluded “No similar trends were found with past intake of milk or milk products” [3]. Food Cal-Mag Complex contains vegetables and fruit/s, but no rocks, milk, or milk products.

Specific Conclusions from Scientific Research

Often we attempt to meet our mineral requirements through consuming processed rocks known as mineral salts. But most nutrition experts believe that nutrient dense foods are the best way to acquire needed minerals [1,12]. Water thyme (Hydrilla verticillata) is the most mineral dense Food known--and the water thyme (and the other plants) in Food Cal-Mag Complex is harvested around the peak of its mineral density for maximum nutrient content.

Many ‘natural’ products contain inorganic mineral salts instead of Food. These mineral salts are actually inorganic industrial rocks, whose primary use is not human nutrition. Calcium carbonate and silicon dioxide for example are used to manufacture glass, abrasives, and ceramics [13]. Nearly all inorganic ‘magnesium salts’ have a laxative or carthatic affect on the body [13], thus do not seem to be suitable for optimal human nutrition [12]. Magnesium oxide, which is used in certain cements [13], does have not complexed magnesium--complexed magnesium is thankfully better absorbed [11] (foods, of course, contain complexed magnesium [12]) . Manganese sulfate is used to make red dye [13]. Boric acid and sodium borate (boron ‘rocks’) are used for weatherproofing wood, as a preservative, in the manufacture of cements and glass, as well as for cockroach control [13]. Copper sulfate is used as a drain cleaner. Manganese carbonate is used as a whitener as well as for a drier for varnishes [13]. Should you recommend that your clients consume such things?

Foods contain many other substances which can affect bone and joint health, such as trace minerals and the enzyme superoxide dismutase (S.O.D.). S.O.D. appears to reduce articular cartilage damage associated with osteoarthritis [15]. Food sources of silicon appear to be much better absorbed than silicon salts, such as silicate additives [1]. Food vitamin D has antirachitic effects, yet the first USP form developed did not [1]. One study found that consumption of Food calcium raised serum ionic calcium levels by 7 points, while a non-food form did not [9]; raising serum ionic levels has been shown to reduce high blood pressure [9,16].

The question is, since humans do not absorb minerals in rock form such as plants do (this is one of the most basic ways that plants and humans differ [17]), should humans swallow rocks processed with various acids for their mineral needs or consume natural mineral as they are found in plants?

Interestingly in 1999 the Nobel prize in medicine was awarded for the finding that humans need protein chaperones in order for minerals to be absorbed into the cell. Calcium and magnesium mineral salts do not contain protein chaperones, yet Food Cal-Mag Complex naturally contains protein chaperones such as ceruloplasmin and ATX1 [18,19]. Thus being non-foods, typical ‘cal-mag’ formulas are truly inferior to Food Cal-Mag Complex.

Contains naturally occurring carbohydrates, lipids, proteins (including all ten essential amino acids), superoxide dismutase, and truly organic bioflavonoids as found in enzymatically processed Saccharomyces cerevisiae, Water thyme Hydrilla vericillata, Alfalfa Medicago sativa and citrus fruits --all the nutrients shown above are contained in these foods. Unlike many so-called “natural” calcium formulas, Cal-Mag Complex is a true food calcium (not a mineral salt) contains no synthetic USP nutrients or mineral salts, but only contains foods, food complexes,

Numerous university studies have concluded that supplements containing food nutrients are better than USP isolates. Food nutrients are better because they contain important enzymes, peptides, and phytonutrients CRITICAL to the UTILIZATION of vitamins and minerals which are not present in isolated USP nutrients. Published research has concluded that food vitamins are superior synthetic/USP vitamins.

Suggested use: 1-9 tablets per day or as recommended by your health care professional. Adjust usage according to nutritional lifestyle requirements.

Cal-Mag Complex Video
References

[1] Shils ME, Olson JA, Shike M. Modern Nutrition in Health and Disease, 9th ed. Williams & Wilkins, Balt., 1999

[2] Spindler A. Bone mineral density in a native population of Argentina with low calcium intake. J Rheumatol, 1995;22(11):2148-2151

[3] New, SA, et al. Dietary influences on bone mass and bone metabolism: further evidence of a positive link between fruit and vegetable consumption and bone health. Am J Clin Nutr, 2000;71(1):142-151

[4] Tucker KL, Chen H, Hannan MT, Cupples LA, Wilson PW, Felson D, Kiel DP. Bone mineral density and dietary patterns in older adults: the Framington osteoporosis study. Am J Clin Nutr 2002;76(1):245-252

[5] Ha SW. Rabbit study comparing yeast and isolated B vitamins (as described in Murray RP. Natural vs. Synthetic. Mark R. Anderson, 1995, p:A3). Ann Rev Physiol,1941; 3:259-282

[6] Thiel R. Natural vitamins may be superior to synthetic ones. Med Hypo, 2000;55(6):461-469

[7] DeCava JA. The Real Truth About Vitamins & Antioxidants. A Printery, Centerfield (MA), 1997

[8] Biotechnology in the Feed Industry. Nottingham Press, UK, 1995: 257-267

[9] Hamet P, et al. The evaluation of the scientific evidence for a relationship between calcium and hypertension. J Nutr, 1995;125:311S-400S

[10] Thiel R. Vitamin D, rickets, and mainstream experts. Int J Naturopathy, 2003; 2(1)

[11]Traber MG. Vitamin E. In Modern Nutrition in Health and Disease, 9th ed. Williams & Wilkins, 1999:347-362

[12] Rude R.K., Shils M.E. Magnesium. In Modern Nutrition in Health and Disease, 10th ed. Lippincott William & Wilkins, Phil, 2005: 223-247

[13] Budavari, S editor. The Merck Index, 12th ed. Merck & Co., Rahway (NJ), 1997

[14] Lindberg JS, Zobitz MM, Poindexter JR, Pak CY. Magnesium bioavailability from magnesium citrate and magnesium oxide. J Am Coll Nutr 1990;9(1):48-55

[15] Hoedt-Schmidt S. Histomorphological studies on the effect of recombinant human superoxide dismutase exhibited inhibitory effects on the articular cartilage tissue damage associated with osteoarthritis. Pharm 1993, 47(4):25-260

[16] Orlov SN, Li JM, Tremblay J, Hamet P. Genes of intracellular calcium metabolism and blood pressure control in primary hypertension. Semin Nephrol. 1995 Nov;15(6):569-592

[17] Cronquist A. Plantae. In Synopsis and Classification of Living Organisms, Vol. 1. McGraw-Hill, 1982:57

[18] Rouhi AM. Escorting metal ions: protein chaperone protects, guides, copper ions in transit. Chem Eng News, 1999;11:34-35

[19] Himelblau E, et al. Identification of a functional homolog of the yeast copper homeostasis gene ATX1 from Arabidopsis. Plant Physiol 1998;117(4):1227- 1234

[20] Huang Y, Chen Y, Tao S. Effect of rhizospheric environment of VA-mycorrhizal plants on forms of Cu, Zn, PB and Cd in polluted soil. Ying Yong Sheng Tai Xye Bao 2000;11(3):431-434

Some of these studies (or citations) may not conform to peer review standards, therefore, the results are not conclusive. Professionals can, and often do, come to different conclusions when reviewing scientific data. None of these statements have been reviewed by the FDA. All products by Doctors’ Research, Inc. are nutritional and are not intended for the treatment or prevention of any medical condition.